Stratford Road is a major commuter route into the city centre of Birmingham, which was blocked following a two-vehicle pile-up at a busy junction.
Two men were seriously hurt and a third man was arrested on suspicion of drink driving.
The crash transpired on the A34 at the Kyotts Lake Road junction and the Sratford Road in Sparkbrook at 6.49am today.
A man was stuck inside one of the vehicles which meant that fire crews had to use expert cutting equipment to free him from the wreckage.
Another man was also hurt.
Both men, aged 49 and 32, were taken to hospital for treatment.
The main Stratford Road was closed between Henley Street and Farm Road.
Emergency services operated at the scene to treat the crash victims and ensure that the vehicles were safe.
The police have announced that the road will remain sealed off throughout the morning. Motorists and bus services are being diverted.
A spokesman for West Midlands Fire Service said: “We were alerted to the crash by the ambulance service.
“One man was trapped by his injuries and crews used cutting equipment to free him from his car.
“When he was out of the car he was given first aid by paramedics and taken to hospital. The extent of his injuries is not known.”
Police have said that a 29-year-old man was arrested on suspicion of drink driving.
